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Mathew and Noelia attend the 6th Japan-UK Neuroscience Meeting in Awaji, Osaka

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Mathew and Noelia were recently invited to attend the Japan-UK neuroscience meeting being held in Osaka, Japan. The meeting, jointly funded by AMED and MRC, sought to strengthen connections between researchers in the UK and Japan. The meeting was a fantastic opportunity to share their research, and also learn about other work being conducted by neuroscientists in the two countries. Delegates were also treated to trip to a local castle, and were serenaded by talented singers in an impromptu Karaoke bar visit!
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New assay for screening membrane-permeabilising peptides and proteins published in Angewandte Chemie International Edition

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Researchers from the ESMB have developed a single-molecule liposome assay that promises to transform the study of membrane disruption by proteins and peptides. Their innovative method, funded by the Leverhulme Trust, addresses longstanding challenges in membrane-related research across antimicrobial activity, toxicity, and disease pathology. Membrane integrity is crucial for cellular health, playing a vital role in processes such as ion transport and signal transmission. Disruption of these membranes is linked to various disorders, including Alzheimer's and Parkinson’s disease, and certain cancers. Traditional techniques for examining the membrane-disrupting effects of proteins and peptides can be challenging and often require larger quantities, which are costly and difficult to produce. Their new approach uses single-molecule confocal microscopy with fast-flow microfluidics to detect membrane disruption with minimal quantities of proteins and peptides. This method provides unparal...
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