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Synuclein meeting 2025 in Cambridge

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  Last week, some members of the ESMB group attended the Synuclein meeting 2025 to hear about current and future approaches to target synulceinopathies. This event offered a very varied programme, with talks ranging from clinical and pre-clinical studies in the field of Parkinson’s disease and Multiple System Atrophy all the way to super-resolution imaging of aSynuclein aggregates. It was an amazing experience to get to hear from groups that have changed this field over the years and also to see all the new projects being set up to study these diseases onset and progression, therapies and diagnosis. It felt like going back to the origins of the group, where it all started! Finally, Gala dinner/party at King’s College Hall was definitely a highlight of the programme.
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Zoe wins a Sir William Darling Memorial Prize for enhancing the reputation of the University of Edinburgh

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Huge congratulations to Zoe Gidden, who has been awarded a Sir William Darling Memorial Prize of £1000. Traditionally, this Prize is awarded to an individual or group of students who have done most to enhance the reputation of the University. Zoe has done this firstly through her role on the University swim team, which has resulted in her winning multiple events: Scottish National Masters Champion 2021 25-29 yrs in 50m butterfly, 50m freestyle, 100m freestyle, 200m freestyle and 100m individual medley. Achieving times that were faster than the Scottish age group record in the 50m and 100m freestyle. Scottish National Masters Champion 2022 25-29 yrs in 50m butterfly, 50m freestyle, 100m freestyle and 100m individual medley. Again, achieving times faster than the Scottish age group record in the 50m and 100m freestyle. Represented the University of Edinburgh in Scottish Student Sport League Division 1 matches. In addition to her sporting achievements, Zoe has also enhanced the reputation...
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A new tool to detect and diagnose disease from blood samples

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We have developed an innovative method to detect small biological particles in blood samples, opening up new possibilities for earlier and more accurate disease diagnosis.  The technique, which we refer to as VISTA (Vesicle Imaging by Single-molecule TCCD Analysis), allows scientists to characterise tiny particles called extracellular vesicles (EVs), which are released by cells into the blood.  “This new tool is of huge potential, offering an easy way to obtain information from patient blood samples, without the need for invasive biopsies.” - Noelia. EVs carry molecular information of their cells of origin and are increasingly recognised as potential biomarkers for diseases such as cancer, Parkinson’s disease, and infections. However, because EVs are highly variable, and similar in size to other particles in the blood, they have been difficult to study using traditional methods. This new approach combines fluorescent labelling (to make EVs glow), microfluidics (a system that m...
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